In recent years, more and more researchers presented their graphic representations for protein sequence.
Here, we present a new 2D graphic representation of protein sequence based on four physicochemical
properties of 20 amino acids. By this graphic representation we define a distance calculation formula
to quantificationally calculate the similarity degree of different protein sequences. Then we apply the
proposed graphical curve and new distance in the similarity/dissimilarity comparison of 10 ND5 proteins
and the protein sub-cellular localization prediction about two common test datasets, ZD98 and CL317.
The results show the proposed method is easy and effective.
